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Literature summary for 3.4.21.69 extracted from
- Recombinant human activated protein C (Xigris) attenuates murine cerulein-induced acute pancreatitis via regulation of nuclear factor kappaB and apoptotic pathways (2012), Pancreas, 41, 619-628.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood plasma | - |
Homo sapiens | - |
| commercial preparation | recombinant enzyme | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Activated protein C | - |
Homo sapiens |
| APC | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | microvascular thrombosis occurs in severe acute pancreatitis, injection of recombinnat activated protein C in a rat model does not modify coagulation parameters or lead to hemorrhage but ameliorates pancreatic injury with preservation of IkappaB and reduction of NF-kappaB p65 and modulation of apoptosis, overview | Homo sapiens |
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Release 2023.1 (January 2023)
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