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Literature summary for 3.4.21.69 extracted from

  • Brueckmann, M.; Nahrup, A.S.; Lang, S.; Bertsch, T.; Fukudome, K.; Liebe, V.; Kaden, J.J.; Hoffmann, U.; Borggrefe, M.; Huhle, G.
    Recombinant human activated protein C upregulates the release of soluble fractalkine from human endothelial cells (2006), Br. J. Haematol., 133, 550-557.
    View publication on PubMed
Search for more literature for 3.4.21.69

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 x * 55000, recombinant activated enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the activated protein C constitutes an important natural coagulation inhibitor and key regulator of both coagulation and inflammation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation recombinant activated enzyme Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the activated protein C constitutes an important natural coagulation inhibitor and key regulator of both coagulation and inflammation Homo sapiens ?
-
 ?
additional information recombinant activated protein C upregulates the release of soluble fractalkine, a unique endothelial cell-derived chemokine that functions both as a chemoattractant and as an adhesion molecule, from human umbilical vein endothelial cells about 2.5fold, PAR-1- and PAR-2-agonist peptides stimulate the fractalkine release, the protein C zymogen is inactive, overview Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, recombinant activated enzyme Homo sapiens

Synonyms

Synonyms Comment Organism
Activated protein C
-
 Homo sapiens
rhAPC
-
 Homo sapiens