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Literature summary for 3.4.21.69 extracted from
- Monocytes, but not endothelial cells, downregulate the anticoagulant activity of activated protein C (2001), Br. J. Haematol., 112, 519-526.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Factor VIIIa + H2O | Homo sapiens | natural anticoagulant, inhibits thrombin generation by degrading factors Va and VIIIa | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Factor Va + H2O | natural anticoagulant, inhibits thrombin generation by degrading factors Va and VIIIa | Homo sapiens | ? | - |
? | |
| Factor VIIIa + H2O | natural anticoagulant, inhibits thrombin generation by degrading factors Va and VIIIa | Homo sapiens | ? | - |
? | |
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Release 2023.1 (January 2023)
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