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Literature summary for 3.4.21.68 extracted from
- Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection (2019), Microbes Infect., 21, 412-417 .
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | tPA-deficient ALBPLG1 mice show no difference in survival, bacterial dissemination or the pathology of GAS infection in the absence of tPA in AlbPLG1/tPA-/- mice compared to wild-type AlbPLG1 mice | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P11214 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Tissue-type plasminogen activator | - |
Mus musculus |
| tPA | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | tPA-deficient ALBPLG1 mice show no difference in survival, bacterial dissemination or the pathology of GAS infection in the absence of tPA in AlbPLG1/tPA-/- mice compared to wild-type AlbPLG1 mice | Mus musculus |
| physiological function | plasmin(ogen) acquisition is critical for invasive disease initiation by Streptococcus pyogenes (GAS), limited role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection | Mus musculus |
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Release 2023.1 (January 2023)
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