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Literature summary for 3.4.21.68 extracted from

  • Mahboudi, F.; Barkhordari, F.; Godarzi, R.M.; Enayati, S.; Davami, F.
    A fed-batch based cultivation mode in Escherichia coli results in improved specific activity of a novel chimeric-truncated form of tissue plasminogen activator (2013), J. Appl. Microbiol., 114, 364-372.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
recombinant expression of the chimeric truncated mutant enzyme using the CHO ATCC CRL9606 expression system, and as soluble His-tagged enzyme in Escherichia coli BL21(DE3) strain with F- dcm ompT hsdS (rB- mB-) gal genotype, comparison of protein potency in batch and fed-batch processes of the two methods, overview Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information construction of a chimeric-truncated form of tissue-type plasminogen activator with improved fibrin affinity and resistance to plasminogen activator inhibitor-1 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
plasminogen activator inhibitor-1 PAI Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P00750
-
-

Synonyms

Synonyms Comment Organism
t-PA
-
Homo sapiens
Tissue plasminogen activator
-
Homo sapiens