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Literature summary for 3.4.21.61 extracted from

  • Han, H.E.; Rho, S.H.; Lee, Y.J.; Park, W.J.
    Engineering of Kex2 variants exhibiting altered substrate specificity (2005), Biochem. Biophys. Res. Commun., 337, 1102-1106.
    View publication on PubMed
Search for more literature for 3.4.21.61

Protein Variants

Protein Variants Comment Organism
D176G/D210A/D211S no preference for positively charged residues at P2 position, and S2 pocket is more solvent accessible, leading to preference for MR- over LR- or FR-containing substrates Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
 Saccharomyces cerevisiae 5794
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information wild-type, preference for positively charged residues at P2 position. Mutant D176G/D210A/D211S, preference for MR- over LR- or FR-containing substrates, which cannot be cleaved by wild-type Saccharomyces cerevisiae ?
-
 ?