Literature summary for 3.4.21.61 extracted from

Rockwell, N.C.; Krysan, D.J.; Fuller, R.S.
Synthesis of Peptidyl Methylcoumarin Esters as Substrates and Active-Site Titrants for the Prohormone Processing Proteases Kex2 and PC2 (2000), Anal. Biochem., 280, 201-208.

Search for more literature for 3.4.21.61

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.023	-	benzyloxycarbonyl-Ala-Tyr-Lys-Lys 4-methylcoumarin 7-amide	pH 7.0, 21°C	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	yeast	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzyloxycarbonyl-Ala-Tyr-Lys-Lys 4-methylcoumarin 7-amide + H2O	-	Saccharomyces cerevisiae	7-amino-4-methylcoumarin + benzyloxycarbonyl-Ala-Tyr-Lys-Lys	-	?
benzyloxycarbonyl-Nle-Tyr-Lys-Lys 4-methylcoumarin 7-amide + H2O	-	Saccharomyces cerevisiae	7-amino-4-methylcoumarin + Cbz-Nle-Tyr-Lys-Lys	-	?

Synonyms

Synonyms	Comment	Organism
prohormone processing protease	-	Saccharomyces cerevisiae

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
2640	-	benzyloxycarbonyl-Ala-Tyr-Lys-Lys 4-methylcoumarin 7-amide	pH 7.0, 21°C	Saccharomyces cerevisiae

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)