Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.6 extracted from

  • Fadeeva, O.A.; Panteleev, M.A.; Karamzin, S.S.; Balandina, A.N.; Smirnov, I.V.; Ataullakhanov, F.I.
    Thromboplastin immobilized on polystyrene surface exhibits kinetic characteristics close to those for the native protein and activates in vitro blood coagulation similarly to thromboplastin on fibroblasts (2010), Biochemistry (Moscow), 75, 734-743.
    View publication on PubMed
Search for more literature for 3.4.21.6

Activating Compound

Activating Compound Comment Organism Structure
tissue factor i.e. thromboplastin Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
 Homo sapiens 9986
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification factor X is converted into its active form, factor Xa, in response to the factor VIIa-tissue factor, i.e. thromboplastin, complex, overview. Kinetics of immobilized tissue factor binding to factor VIIa compared to non-immobilzed one, overview. Immobilization of the tissue factor on the surface has no qualitative effect on the kinetics of tissue factor interaction with factor VIIa and does not affect the activation activity of factor Xa and the coagulation cascade Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Z-D-Arg-Gly-L-Arg-4-nitroanilide + H2O i.e. S-2765 Homo sapiens Z-D-Arg-Gly-L-Arg + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
factor Xa
-
 Homo sapiens