Literature summary for 3.4.21.6 extracted from

Chandrasekaran, V.; Lee, C.J.; Lin, P.; Duke, R.E.; Pedersen, L.G.
A computational modeling and molecular dynamics study of the Michaelis complex of human protein Z-dependent protease inhibitor (ZPI) and factor Xa (FXa) (2009), J. Mol. Model., 15, 897-911.

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Inhibitors

Inhibitors	Comment	Organism	Structure
antithrombin III	AT3, a member of the serpin superfamily of protease inhibitors, X-ray crystal structure-based simulations of AT3/FXa, PDB code 2GD4, overview	Homo sapiens
protein Z-dependent protease inhibitor	ZPI, UniProt ID Q9UK55, a member of the serpin superfamily of protease inhibitors, ZPI can produce rapid inhibition of FXa in the presence of the not-essential cofactor protein Z, negatively charged phospholipids and Ca2+ ions, mechanism. Generation of a three-dimensional structural model of the Michaelis complex of human ZPI/FXa using homology modeling, protein-protein docking and molecular dynamics simulation methods, overview	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
factor Xa	-	Homo sapiens
FXa	-	Homo sapiens

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Release 2023.1 (January 2023)