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Literature summary for 3.4.21.6 extracted from

  • Rauch, U.
    Rivaroxaban - once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and embolism trial in atrial fibrillation: rationale and design of the ROCKET AF study (2010), Am. Heart J., 159, 340-347.e1.
    View publication on PubMed

Application

Application Comment Organism
drug development the enzyme is a target for drug development in prevention and treatment of thromboembolic disorders, overview Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
rivaroxaban an oral direct factor Xa inhibitor, in advanced development as an alternative to warfarin for the prevention and treatment of thromboembolic disorders Homo sapiens
warfarin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
factor Xa
-
Homo sapiens

General Information

General Information Comment Organism
malfunction enzyme inhibition is beneficial in prevention and treatment of thromboembolic disorders Homo sapiens