Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-matrix metalloproteinase-2 + H2O | Homo sapiens | - |
matrix metalloproteinase-2 + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | significantly more tryptase in peritumoral tissue than in normal breast tissue | Homo sapiens | - |
MDA-MB-231 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-matrix metalloproteinase-2 + H2O | - |
Homo sapiens | matrix metalloproteinase-2 + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Mast cell tryptase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | increased tryptase is associated with higher tumor grade and more lymph node metastasis in breast cancer tissue | up |
General Information | Comment | Organism |
---|---|---|
physiological function | tryptase promotes the invasion and migration of breast cancer cells along with activation of matrix metalloproteinase-2. Tryptase does not affect the proliferation of the cells. Tryptase promotes breast cancer migration and invasion | Homo sapiens |