Literature summary for 3.4.21.59 extracted from

Cregar, L.; Elrod, K.C.; Putnam, D.; Moore, W.R.
Neutrophil myeloperoxidase is a potent and selective inhibitor of mast cell tryptase (1999), Arch. Biochem. Biophys., 366, 125-130.

Search for more literature for 3.4.21.59

Application

Application	Comment	Organism
medicine	potent and selective inhibitor of tryptase will be an essential tool to determine the role of tryptase in inflammation and other processes, tryptase plays a role in asthma and other allergic and inflammatory skin diseases like psoriasis and atopic dermatitis	Homo sapiens

General Stability

General Stability	Organism
stabilized by heparin proteoglycans	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
neutrophil myeloperoxidase	important component of the neutrophil response to microbial infection, high concentrations of heparin can prevent the inhibition of tryptase by MPO	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
secretory granule	-	Homo sapiens	30141	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	human	-

Synonyms

Synonyms	Comment	Organism
Mast cell tryptase	-	Homo sapiens

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Release 2023.1 (January 2023)