Literature summary for 3.4.21.5 extracted from

Bezaud, A.; Guillin, M.C.
Enzymic and nonenzymic properties of human beta-thrombin (1988), J. Biol. Chem., 263, 3576-3581.

Search for more literature for 3.4.21.5

Inhibitors

Inhibitors	Comment	Organism	Structure
benzamidine	-	Homo sapiens
diisopropyl fluorophosphate	unlike alpha-thrombin, beta-thrombin is not protected from inhibition by diisopropyl fluorophosphate in the presence of fibrinogen	Homo sapiens
tosyl-Lys chloromethyl ketone	-	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0021	-	D-Phe-L-pipecolyl-L-Arg-4-nitroanilide	alpha-thrombin	Homo sapiens
0.00232	-	D-Phe-L-pipecolyl-L-Arg-4-nitroanilide	beta-thrombin	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-Phe-L-pipecolyl-L-Arg-4-nitroanilide + H2O	-	Homo sapiens	D-Phe-L-pipecolyl-L-Arg + 4-nitroaniline	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
56.5	-	D-Phe-L-pipecolyl-L-Arg-4-nitroanilide	beta-thrombin	Homo sapiens
77.8	-	D-Phe-L-pipecolyl-L-Arg-4-nitroanilide	alpha-thrombin	Homo sapiens

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Release 2023.1 (January 2023)