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BRENDA support

Literature summary for 3.4.21.5 extracted from

  • Parrales, A.; Palma-Nicolas, J.P.; Lopez, E.; Lopez-Colome, A.M.
    Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression (2010), J. Cell. Physiol., 222, 302-312.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fibrinogen + H2O Homo sapiens
-
fibrin + fibrinopeptide A + fibrinopeptide B
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrinogen + H2O
-
Homo sapiens fibrin + fibrinopeptide A + fibrinopeptide B
-
?

General Information

General Information Comment Organism
physiological function thrombin stimulates retinal pigment epithelium cell proliferation by promoting c-Fos-mediated cyclin D1 expression, thrombin induces the biphasic expression of c-Fos Homo sapiens