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Literature summary for 3.4.21.5 extracted from

  • James, C.; Collison, D.J.; Duncan, G.
    Characterization and functional activity of thrombin receptors in the human lens (2005), Invest. Ophthalmol. Vis. Sci., 46, 925-932.
    View publication on PubMed

Application

Application Comment Organism
medicine exposure to thrombin induces an increase in cytosolic calcium in both anterior and equatorial lens cells. Repeated exposure produces a significant increase in cell coverage in the capsular bag model and increased thymidine incorporation into FHL124 cells. In FHL124 cells, exposure to thrombin induces biphasic increases in the phosphorylation of p42/p44 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
lens human capsular bag model Homo sapiens
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