Literature summary for 3.4.21.47 extracted from

Ganter, M.T.; Brohi, K.; Cohen, M.J.; Shaffer, L.A.; Walsh, M.C.; Stahl, G.L.; Pittet, J.F.
Role of the alternative pathway in the early complement activation following major trauma (2007), Shock, 28, 29-34.

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Application

Application	Comment	Organism
medicine	clinical significance of early complement stimulation in trauma patients analyzed, complement stimulation, particularly alternative pathway related to clinical outcomes in patients with severe trauma	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P00751	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
plasma	trauma patients, clinical characteristics shown	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	plasma levels of complement components determined in patients with severe trauma	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	early complement stimulation in trauma patients analyzed, correlation with injury severity, tissue hypoperfusion and worse clinical outcomes identified	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
C3 convertase	-	Homo sapiens

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Release 2023.1 (January 2023)