Activating Compound | Comment | Organism | Structure |
---|---|---|---|
zymosan | it is capable of activating the classical pathway as well as the alternative pathway, when the classical pathway is blocked, mechanism, overview | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
C1 inhibitor | blocks the the classical pathway | Homo sapiens | |
C4d antibody | blocks the the classical pathway | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
C3 convertase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | zymosan activates the classical pathway by an antigen-antibody reaction in normal human serum requiring IgG and IgM antibodies, it cannot initiate classical pathway activation without the antibodies, regulation, overview | Homo sapiens |