Inhibitors | Comment | Organism | Structure |
---|---|---|---|
extracellular complement-binding protein | Ecb, a potent complement inhibitor from Staphylococcus aureus, with strong antiinflammatory properties, inhibitory mechanism for blocking C3b-containing convertases, Efb-C and Ecb act on the bacterial surface, overview | Homo sapiens | |
extracellular fibrinogen-binding protein | Efb, a potent complement inhibitor from Staphylococcus aureus, with strong antiinflammatory properties, inhibitory mechanism for blocking C3b-containing convertases, Efb-C and Ecb act on the bacterial surface, overview | Homo sapiens | |
staphylococcal complement inhibitor | SCIN, a potent complement inhibitor from Staphylococcus aureus, with strong antiinflammatory properties, inhibitory mechanism for blocking C3b-containing convertases, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement component C5 + H2O | Homo sapiens | C5 convertases C4b2aC3b and C3b 2 Bb | complement component C5a + complement component C5b | - |
? | |
complement componentC3 + H2O | Homo sapiens | C3 convertase C3bBb | complement component C3a + complement component C3b | - |
? | |
additional information | Homo sapiens | the alternative pathway lead via C3 convertase C3bBb and the C5 convertases C4b2aC3b and C3b 2 Bb | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement component C5 + H2O | C5 convertases C4b2aC3b and C3b 2 Bb | Homo sapiens | complement component C5a + complement component C5b | - |
? | |
complement componentC3 + H2O | C3 convertase C3bBb | Homo sapiens | complement component C3a + complement component C3b | - |
? | |
additional information | the alternative pathway lead via C3 convertase C3bBb and the C5 convertases C4b2aC3b and C3b 2 Bb | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
C3 convertase | - |
Homo sapiens |
C3b 2 Bb | - |
Homo sapiens |
C3bBb | - |
Homo sapiens |
C4b2aC3b | - |
Homo sapiens |
C5 convertase | - |
Homo sapiens |