Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-carboxylic acid | - |
Rattus norvegicus | |
4-(biphenyl-3-ylsulfonyl)-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(2'-chlorobiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(2'-ethenylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(2'-hydroxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(2'-methoxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(2'-methylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(2-amino-6-methylphenyl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(3'-hydroxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(3'-methoxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(3'-methylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(3-bromophenyl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(4'-hydroxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(4'-methoxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[(4'-methylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[[2'-(hydroxymethyl)-6'-methylbiphenyl-3-yl]sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[[2'-(hydroxymethyl)biphenyl-3-yl]sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
4-[[3-(3-methylpyridin-2-yl)phenyl]sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
5-(methylsulfanyl)-4-[[2'-methyl-6'-([[2-(2H-tetrazol-5-yl)ethyl]carbamoyl]amino)biphenyl-3-yl]sulfonyl]thiophene-2-carboximidamide | - |
Rattus norvegicus | |
6-[(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)amino]-6-oxohexanoic acid | - |
Rattus norvegicus | |
6-[[(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)carbamoyl]amino]hexanoic acid | - |
Rattus norvegicus | |
C1-esterase inhibitor | - |
Rattus norvegicus | |
N-(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)-2-(methylsulfonyl)acetamide | - |
Rattus norvegicus | |
N-(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)-4-(methylsulfonyl)butanamide | - |
Rattus norvegicus | |
tert-butyl [[4-[(3-bromophenyl)sulfonyl]-5-(methylsulfanyl)thiophen-2-yl](imino)methyl]carbamate | binding mode in the active site, structure, overview | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
complement component C1s | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000012 | - |
N-(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)-2-(methylsulfonyl)acetamide | - |
Rattus norvegicus | |
0.000014 | - |
N-(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)-4-(methylsulfonyl)butanamide | - |
Rattus norvegicus | |
0.00002 | - |
4-[(2-amino-6-methylphenyl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.000022 | - |
6-[[(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)carbamoyl]amino]hexanoic acid | - |
Rattus norvegicus | |
0.00003 | - |
4-[(2'-methylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00004 | - |
4-[(2'-chlorobiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00004 | - |
4-[[3-(3-methylpyridin-2-yl)phenyl]sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.000042 | - |
6-[(3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-yl)amino]-6-oxohexanoic acid | - |
Rattus norvegicus | |
0.00005 | - |
4-[[2'-(hydroxymethyl)-6'-methylbiphenyl-3-yl]sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.000064 | - |
5-(methylsulfanyl)-4-[[2'-methyl-6'-([[2-(2H-tetrazol-5-yl)ethyl]carbamoyl]amino)biphenyl-3-yl]sulfonyl]thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00012 | - |
4-[[2'-(hydroxymethyl)biphenyl-3-yl]sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00014 | - |
4-[(2'-ethenylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00015 | - |
3'-[[5-carbamimidoyl-2-(methylsulfanyl)thiophen-3-yl]sulfonyl]-6-methylbiphenyl-2-carboxylic acid | - |
Rattus norvegicus | |
0.00015 | - |
4-[(3'-hydroxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00019 | - |
4-[(4'-hydroxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00025 | - |
4-[(4'-methylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00026 | - |
4-(biphenyl-3-ylsulfonyl)-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00035 | - |
4-[(4'-methoxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00036 | - |
4-[(3-bromophenyl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00046 | - |
4-[(2'-hydroxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00049 | - |
4-[(3'-methoxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00061 | - |
4-[(2'-methoxybiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus | |
0.00185 | - |
4-[(3'-methylbiphenyl-3-yl)sulfonyl]-5-(methylsulfanyl)thiophene-2-carboximidamide | - |
Rattus norvegicus |