Application | Comment | Organism |
---|---|---|
medicine | the enzyme represents a pivotal upstream point of control in the classical pathway of complement activation and is therefore likely to be a useful target in the therapeutic intervention of diseases like hereditary angioedema, ischemia-reperfusion injury and acute transplant rejection | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | optimization of thiopheneamidine-based inhibitors | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme represents a pivotal upstream point of control in the classical pathway of complement activation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme represents a pivotal upstream point of control in the classical pathway of complement activation | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
protease C1s | - |
Homo sapiens |