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Literature summary for 3.4.21.41 extracted from

  • Gal, P.; Zavodzky, P.
    Structure and function of the serine-protease subcomponents of C1: protein engineering studies (1998), Immunobiology, 199, 317-326.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in insect cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
R463X construction of a stable zymogen by mutating the Arg463Ile bond shows that one active C1r in the C1 complex is sufficient for the full activity of the entire complex Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification the zymogen C1r is a glycoprotein Homo sapiens