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Literature summary for 3.4.21.4 extracted from

  • McGrath, M.E.; Haymore, B.L.; Summers, N.L.; Craik, C.S.; Fletterick, R.J.
    Structure of an engineered, metal-actuated switch in trypsin (1993), Biochemistry, 32, 1914-1919.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
X-ray crystal structure of trypsin R96H at pH 8.0 in the presence of CuCl2 Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
additional information effective inhibition of the catalytic activity by metal ions observed in trypsin R96H is caused by specific and reversible reorganization of the active site in the enzyme Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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