Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | identification of trypsin-3 binding peptides, and molecular modeling of the binding of peptides to isozyme trypsin-3. The degradation rate of peptides by trypsin correlates to their inhibitory efficacy, the most stable peptides being the most effective inhibitors, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isozymes trypsin-1, -2, -C and -3 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | trypsin is produced as a proenzyme, trypsinogen, mainly by the pancreas, and it is activated in the gastrointestinal tract by enterokinase | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | trypsinogen is expressed in various other healthy and malignant tissues | Homo sapiens | - |
pancreas | trypsin is produced as a proenzyme, trypsinogen, mainly by the pancreas, and it is activated in the gastrointestinal tract by enterokinase | Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-casein + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | cleavage of the potentially inhibitory peptides by isozyme trypsin-3, substrate specificity, overview | Homo sapiens | ? | - |
? | |
S-2222 + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TRY-3 | - |
Homo sapiens |
trypsin-3 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | active trypsin participates in the digestion of food by degradation of dietary proteins and by activation of other digestive enzymes in the small intestine | Homo sapiens |