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Literature summary for 3.4.21.4 extracted from

  • Elphick, D.; Liddell, S.; Mahida, Y.R.
    Impaired luminal processing of human defensin-5 in Crohns disease: persistence in a complex with chymotrypsinogen and trypsin (2008), Am. J. Pathol., 172, 702-713.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
alpha1-antitrypsin
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the sequence of trypsin is IVGGY ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ileostomal fluid
-
Homo sapiens
-
paneth cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the sequence of trypsin is IVGGY Homo sapiens ?
-
?
pro-human defensin-5 + H2O pro-human defensin-5 in the intestinal lumen is processed by trypsin in a complex in which chymotrypsinogen is also cleaved for activation Homo sapiens human defensin-5 + pro-human defensin-5 propeptide
-
?