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Literature summary for 3.4.21.4 extracted from
- The kinetic and structural characterization of the reaction of nafamostat with bovine pancreatic trypsin (2000), Thromb. Res., 98, 559-569.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 6-amidino-2-naphthol | mixed-type inhibition | Bos taurus |  |
| additional information | 4-guanidinebenzoate: no inhibition up to 0.2 mM | Bos taurus | |
| Nafamostat | potent inhibitor | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Nafamostat + H2O | extremely poor substrate | Bos taurus | ? | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.026 | - |
Nafamostat | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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