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Literature summary for 3.4.21.39 extracted from

  • Lipitsae, T.; Siiskonen, H.; Naukkarinen, A.; Harvima, I.T.
    Mast cell chymase degrades fibrinogen and fibrin (2019), Br. J. Dermatol., 181, 296-303 .
    View publication on PubMed
Search for more literature for 3.4.21.39

Activating Compound

Activating Compound Comment Organism Structure
heparin heparin enhances the degradation of the beta-chain of fibrinogen Homo sapiens

Application

Application Comment Organism
medicine the fibrinolytic enzyme with anticoagulative properties may aid in the clearance of fibrin from vessel walls in aged vasculitis lesions Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C3 + H2O Homo sapiens
-
 ?
-
 ?
complement component C3a + H2O Homo sapiens
-
 ?
-
 ?
Fibrin + H2O Homo sapiens
-
 ?
-
 ?
fibrinogen + H2O Homo sapiens chymase degrades the alpha-, beta- and gamma-chains of fibrinogen, while heparin enhances the degradation of the beta-chain fibrin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C3 + H2O
-
 Homo sapiens ?
-
 ?
complement component C3a + H2O
-
 Homo sapiens ?
-
 ?
Fibrin + H2O
-
 Homo sapiens ?
-
 ?
fibrinogen + H2O chymase degrades the alpha-, beta- and gamma-chains of fibrinogen, while heparin enhances the degradation of the beta-chain Homo sapiens fibrin + ?
-
 ?

Synonyms

Synonyms Comment Organism
mast cell chymase
-
 Homo sapiens