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Literature summary for 3.4.21.39 extracted from

  • de Souza Junior, D.A.; Santana, A.C.; da Silva, E.Z.; Oliver, C.; Jamur, M.C.
    The role of mast cell specific chymases and tryptases in tumor angiogenesis (2015), BioMed Res. Int., 2015, 142359 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.39

Inhibitors

Inhibitors Comment Organism Structure
chymostatin
-
 Homo sapiens
chymostatin
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensin I + H2O Mus musculus
-
 angiotensin II + His-Leu
-
 ?
angiotensin I + H2O Homo sapiens
-
 angiotensin II + His-Leu
-
 ?
big-endothelin-1 + H2O Mus musculus
-
 ?
-
 ?
big-endothelin-1 + H2O Homo sapiens
-
 ?
-
 ?
big-endothelin-2 + H2O Mus musculus
-
 ?
-
 ?
big-endothelin-2 + H2O Homo sapiens
-
 ?
-
 ?
pro-matrix metalloproteinase-9 + H2O Mus musculus
-
 matrix metalloproteinase-9 + ?
-
 ?
pro-matrix metalloproteinase-9 + H2O Homo sapiens
-
 matrix metalloproteinase-9 + ?
-
 ?
procollagen + H2O Mus musculus
-
 collagen + ?
-
 ?
procollagen + H2O Homo sapiens
-
 collagen + ?
-
 ?
thrombin + H2O Mus musculus
-
 ?
-
 ?
thrombin + H2O Homo sapiens
-
 ?
-
 ?
tissue inhibitor of metalloproteinase-1 + H2O Mus musculus
-
 ?
-
 ?
tissue inhibitor of metalloproteinase-1 + H2O Homo sapiens
-
 ?
-
 ?
transforming growth factor-beta1 + H2O Mus musculus
-
 ?
-
 ?
transforming growth factor-beta1 + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
 Mus musculus
-
mast cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
 Mus musculus angiotensin II + His-Leu
-
 ?
angiotensin I + H2O
-
 Homo sapiens angiotensin II + His-Leu
-
 ?
big-endothelin-1 + H2O
-
 Mus musculus ?
-
 ?
big-endothelin-1 + H2O
-
 Homo sapiens ?
-
 ?
big-endothelin-2 + H2O
-
 Mus musculus ?
-
 ?
big-endothelin-2 + H2O
-
 Homo sapiens ?
-
 ?
pro-matrix metalloproteinase-9 + H2O
-
 Mus musculus matrix metalloproteinase-9 + ?
-
 ?
pro-matrix metalloproteinase-9 + H2O
-
 Homo sapiens matrix metalloproteinase-9 + ?
-
 ?
procollagen + H2O
-
 Mus musculus collagen + ?
-
 ?
procollagen + H2O
-
 Homo sapiens collagen + ?
-
 ?
thrombin + H2O
-
 Mus musculus ?
-
 ?
thrombin + H2O
-
 Homo sapiens ?
-
 ?
tissue inhibitor of metalloproteinase-1 + H2O
-
 Mus musculus ?
-
 ?
tissue inhibitor of metalloproteinase-1 + H2O
-
 Homo sapiens ?
-
 ?
transforming growth factor-beta1 + H2O
-
 Mus musculus ?
-
 ?
transforming growth factor-beta1 + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
monomer
-
 Mus musculus
monomer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
CMA1
-
 Homo sapiens
mast cell specific chymase
-
 Mus musculus
mast cell specific chymase
-
 Homo sapiens
MCP-1 isoform Mus musculus
MCP-4 isoform Mus musculus

General Information

General Information Comment Organism
physiological function the enzyme plays a role in angiogenesis of tumors Mus musculus
physiological function the enzyme plays a role in angiogenesis of tumors Homo sapiens