Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.39 extracted from

  • Magnusson, S.E.; Pejler, G.; Kleinau, S.; Abrink, M.
    Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis (2009), FASEB J., 23, 875-882.
    View publication on PubMed

Application

Application Comment Organism
medicine MCP-4 has a dual role in the development of autoimmune arthritis, first in the initiation phase of collagen-induced arthritis by stimulating the production of pathogenic immunglobulin G anti-collagen II antibodies, and second in the effector phase of arthritis by stimulating local joint inflammation Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
secretory granule
-
Mus musculus 30141
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
Mus musculus
-

Synonyms

Synonyms Comment Organism
mast cell chymase
-
Mus musculus
mast cell protease-4
-
Mus musculus
MC chymase
-
Mus musculus
MC protease 4
-
Mus musculus
MCP-4
-
Mus musculus