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BRENDA support

Literature summary for 3.4.21.38 extracted from

  • Que, B.G.; Davie, E.W.
    Characterization of a cDNA coding for human factor XII (Hageman Factor) (1986), Biochemistry, 25, 1525-1528.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
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Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification when the contact phase of coagulation or fibrinolysis is initiated, factor XII is converted to factor XIIa by cleavage of a single internal Arg-Val peptide bond. This reaction occurs in the presence of kallikrein, an ionic surface, and high molecular weight kininogen Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining