Literature summary for 3.4.21.38 extracted from

Kuijpers, M.J.; van der Meijden, P.E.; Feijge, M.A.; Mattheij, N.J.; May, F.; Govers-Riemslag, J.; Meijers, J.C.; Heemskerk, J.W.; Renne, T.; Cosemans, J.M.
Factor XII regulates the pathological process of thrombus formation on ruptured plaques (2014), Arterioscler. Thromb. Vasc. Biol., 34, 1674-1680.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
factor XIIa	-	Mus musculus
factor XIIa	-	Homo sapiens
FXIIa	-	Mus musculus
FXIIa	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	genetic deficiency in FXII reduces ex vivo whole-blood thrombus and fibrin formation on immobilized plaque homogenates	Mus musculus
malfunction	genetic deficiency in FXII reduces ex vivo whole-blood thrombus and fibrin formation on immobilized plaque homogenates	Homo sapiens
physiological function	factor XII regulates the pathological process of thrombus formation on ruptured plaques. Factor XIIa bound to thrombi ensures thrombus stability	Mus musculus
physiological function	factor XII regulates the pathological process of thrombus formation on ruptured plaques. Factor XIIa bound to thrombi ensures thrombus stability	Homo sapiens

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Release 2023.1 (January 2023)