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Literature summary for 3.4.21.37 extracted from
- Neutrophil elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 receptor antagonist (2016), Sci. Rep., 6, 24880 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| interleukin-36 receptor antagonist + H2O | Homo sapiens | the enzyme cleaves 9 amino acids upstream of the A-X-D consensus of interleukin-36 receptor antagonist | activated interleukin-36 receptor antagonist V2 + ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| neutrophil | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| interleukin-36 receptor antagonist + H2O | the enzyme cleaves 9 amino acids upstream of the A-X-D consensus of interleukin-36 receptor antagonist | Homo sapiens | activated interleukin-36 receptor antagonist V2 + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| neutrophil elastase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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