Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme prefers L-Val in the P1 position but also cleaves substrates with L-Ile relatively efficiently and does not cleave after aromatic amino acids | ? | - |
? | |
additional information | Homo sapiens | the protease shows self-cleaving activity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293-EBNA cell | - |
Homo sapiens | - |
neutrophil | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GRGGAGGRG + H2O | - |
Homo sapiens | GRGGA + GGRG | - |
? | |
GRGGFGGRG + H2O | - |
Homo sapiens | GRGGF + GGRG | - |
? | |
GRGGLGGRG + H2O | - |
Homo sapiens | GRGGL + GGRG | - |
? | |
GRGGRGGRG + H2O | - |
Homo sapiens | GRGGR + GGRG | - |
? | |
GRGGVGGRG + H2O | - |
Homo sapiens | GRGGV + GGRG | - |
? | |
additional information | the enzyme prefers L-Val in the P1 position but also cleaves substrates with L-Ile relatively efficiently and does not cleave after aromatic amino acids | Homo sapiens | ? | - |
? | |
additional information | the protease shows self-cleaving activity | Homo sapiens | ? | - |
? | |
additional information | no activity with succiny-Ala-Ala-Pro-Phe-4-nitroanilide, succiny-Leu-Leu-Val-Tyr-4-nitroanilide, succiny-Ala-Ala-Pro-Leu-4-nitroanilide, succiny-Val-Leu-Gly-Arg-4-nitroanilide, Z-Gly-Pro-Arg-4-nitroanilide, acetyl-Tyr-Val-Ala-Asp-4-nitroanilide, acetyl-Val-Glu-Ile-Asp-4-nitroanilide, and acetyl-Ile-Glu-Pro-Asp-4-nitroanilide | Homo sapiens | ? | - |
? | |
succinyl-Ala-Ala-Pro-Ala-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
succinyl-Ala-Ala-Pro-Ile-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
succinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
VLLFSEVL + H2O | - |
Homo sapiens | VLLF + SEVL | - |
? | |
VLLISEVL + H2O | - |
Homo sapiens | VLLI + SEVL | - |
? | |
VLLVSEVL + H2O | - |
Homo sapiens | VLLV + SEVL | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 30000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
HNE | - |
Homo sapiens |
N-elastase | - |
Homo sapiens |
neutrophil elastase | - |
Homo sapiens |