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Literature summary for 3.4.21.37 extracted from
- Neutrophil elastase causes tissue damage that decreases host tolerance to lung infection with Burkholderia species (2014), PLoS Pathog., 10, e1004327.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | Mus musculus | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | - |
Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| neutrophil elastase | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | absence of neutrophil elastase increases host tolerance, rather than resistance, to lung infection with Burkholderia thailandensis and B. pseudomallei by minimizing host tissue damage | Mus musculus |
| physiological function | neutrophil elastase causes tissue damage and increases vascular leakage that decreases host tolerance to lung infection with Burkholderia thailandensis and B. pseudomallei | Mus musculus |
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