Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha1-antitrypsin | physiological inhibitor of neutrophil elastase. HL-60 cells neutralize neutrophil elastase activity by concomitant secretion of alpha1-antitrypsin | Homo sapiens | |
sivelestat sodium | neutrophil elastase specific inhibitor | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O | - |
Homo sapiens | N-methoxysuccinyl-Ala-Ala-Pro-Val + 4-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Elane | - |
Homo sapiens |
neutrophil elastase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | enzymatic activity of neutrophil elastase is markedly decreased until four hours after the stimulation with lipopolysaccharide | up |