Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | neutrophil elastase does not cleave the N-terminal domains and does not disarm either PAR-1 or PAR-2 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelial cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | neutrophil elastase does not cleave the N-terminal domains and does not disarm either PAR-1 or PAR-2 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
neutrophil elastase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | neutrophil elastase reduces the levels of coagulation factors and inhibits repair of following mechanical wounding of epithelial 16HBE 14o- cell layers. PAR-1 and PAR-2 peptide agonists stimulated the rate of repair and enhanced the formation of a fibrin provisional matrix to support the repair process, overview. But neutrophil elastase does not cleave the N-terminal domains and does not disarm either PAR-1 or PAR-2 | Homo sapiens |