Crystallization (Comment) | Organism |
---|---|
hanging drop vapour diffusion method, using 0.1 M HEPES (pH 7.5) and 20% PEG8000 or in 0.1 M HEPES (pH 7.5) and 35% PEG8000 containing 10 mM N-methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone inhibitor | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,2,5-thiadiazolidin-3-one 1,1-dioxide | the inhibitor causes rapid, time-dependent, irreversible loss of enzymatic activity | Homo sapiens | |
N-methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O | - |
Homo sapiens | N-methoxysuccinyl-Ala-Ala-Pro-Val + 4-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
neutrophil elastase | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00000574 | - |
1,2,5-thiadiazolidin-3-one 1,1-dioxide | - |
Homo sapiens |