Literature summary for 3.4.21.37 extracted from

Alla, V.; Kashyap, A.; Gregor, S.; Theobald, M.; Heid, H.; Galle, P.R.; Strand, D.; Strand, S.
Human leukocyte elastase counteracts matrix metalloproteinase-7 induced apoptosis resistance of tumor cells (2008), Cancer Lett., 268, 331-339.

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Inhibitors

Inhibitors	Comment	Organism	Structure
matrix metalloproteinase-7	human leukocyte elastase cleaves matrix metalloproteinase-7 resulting in loss of enzymatic activity	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
polymorphonuclear leukocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
matrix metalloproteinase-7 + H2O	human leukocyte elastase may be a natural inactivator of matrix metalloproteinase-7 which can counteract matrix metalloproteinase-7-induced apoptosis resistance	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
HLE	-	Homo sapiens

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Release 2023.1 (January 2023)