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Literature summary for 3.4.21.37 extracted from
- The tetraspanin CD63 is involved in granule targeting of neutrophil elastase (2008), Blood, 112, 3444-3454.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | CD63 cooperates in granule delivery of the precursor of neutrophil elastase, depletion of CD63 leads to reduced processing of the precursor of neutrophil elastase into mature neutrophil elastase and reduced constitutive secretion | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| coexpressed with CD63 on COS cells | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Homo sapiens | 5764 | - |
| primary granule | - |
Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| neutrophil | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | - |
Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| neutrophil elastase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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