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Literature summary for 3.4.21.37 extracted from

  • Stein, R.L.; Strimpler, A.M.; Hori, H.; Powers, J.C.
    Catalysis by human leukocyte elastase: mechanistic insights into specificity requirements (1987), Biochemistry, 26, 1301-1305.
    View publication on PubMed
Search for more literature for 3.4.21.37

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0023
-
 methoxysuccinyl-Ala-Ala-Pro-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
0.0023
-
 methoxysuccinyl-Ala-Pro-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
0.012
-
 methoxysuccinyl-Ala-Pro-Ala-thiobenzyl ester pH 7.4, 25°C Homo sapiens
0.012
-
 methoxysuccinyl-Pro-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
0.013
-
 methoxysuccinyl-Ala-Ala-Pro-Ala-thiobenzyl ester pH 7.4, 25°C Homo sapiens
0.015
-
 methoxysuccinyl-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
0.05
-
 methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
0.189
-
 methoxysuccinyl-Ala-Pro-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
0.696
-
 methoxysuccinyl-Pro-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
0.788
-
 methoxysuccinyl-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
0.833
-
 methoxysuccinyl-Ala-Ala-Pro-Ala-4-nitroanilide pH 7.4, 25°C Homo sapiens
1.5
-
 methoxysuccinyl-Ala-Pro-Ala-4-nitroanilide pH 7.4, 25°C Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methoxysuccinyl-Ala-Ala-Pro-Ala-4-nitroanilide
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ala-Pro-Ala-thiobenzyl ester
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ala-Pro-alpha-aminobutyryl-4-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ala-Pro-Val-thiobenzyl ester
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Pro-Ala-4-nitroanilide
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Pro-Ala-thiobenzyl ester
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Pro-Val-4-nitroanilide
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Pro-Val-thiobenzyl ester
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Pro-Val-4-nitroanilide
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Pro-Val-thiobenzyl ester
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Val-4-nitroanilide
-
 Homo sapiens methoxysuccinyl-Val + 4-nitroaniline
-
 ?
methoxysuccinyl-Val-thiobenzyl ester
-
 Homo sapiens ?
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.04
-
 methoxysuccinyl-Pro-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
0.06
-
 methoxysuccinyl-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
7
-
 methoxysuccinyl-Ala-Pro-Ala-4-nitroanilide pH 7.4, 25°C Homo sapiens
10
-
 methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
10
-
 methoxysuccinyl-Ala-Pro-Val-4-nitroanilide pH 7.4, 25°C Homo sapiens
10
-
 methoxysuccinyl-Pro-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
11
-
 methoxysuccinyl-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
13
-
 methoxysuccinyl-Ala-Ala-Pro-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
13
-
 methoxysuccinyl-Ala-Pro-Val-thiobenzyl ester pH 7.4, 25°C Homo sapiens
21
-
 methoxysuccinyl-Ala-Ala-Pro-alpha-aminobutyryl-4-nitroanilide pH 7.4, 25°C Homo sapiens
22
-
 methoxysuccinyl-Ala-Ala-Pro-Ala-4-nitroanilide pH 7.4, 25°C Homo sapiens
46
-
 methoxysuccinyl-Ala-Pro-Ala-thiobenzyl ester pH 7.4, 25°C Homo sapiens
52
-
 methoxysuccinyl-Ala-Ala-Pro-Ala-thiobenzyl ester pH 7.4, 25°C Homo sapiens