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Literature summary for 3.4.21.37 extracted from

  • Nakajima, K.; Powers, J.C.; Ashe, B.M.; Zimmerman, M.
    Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site (1979), J. Biol. Chem., 254, 4027-4032.
    View publication on PubMed
Search for more literature for 3.4.21.37

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.14
-
 methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide pH 7.4, 37°C Homo sapiens
0.31
-
 acetyl-Ala-Ala-Pro-Val-4-nitroanilide pH 7.4, 37°C Homo sapiens
1.7
-
 methoxysuccinyl-Ala-Ile-Pro-Met-4-nitroanilide pH 7.4, 37°C Homo sapiens
2.4
-
 methoxysuccinyl-Ala-Ala-Pro-Met-4-nitroanilide pH 7.4, 37°C Homo sapiens
3.7
-
 N-succinyl-Ala-Ala-Ala 4-nitroanilide pH 7.5, 25°C Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ala-Pro-Met-4-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ile-Pro-Met-4-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
N-succinyl-Ala-Ala-Ala 4-nitroanilide + H2O
-
 Homo sapiens N-succinyl-Ala-Ala-Ala + 4-nitroaniline
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.72
-
 methoxysuccinyl-Ala-Ala-Pro-Met-4-nitroanilide pH 7.4, 37°C Homo sapiens
2.1
-
 N-succinyl-Ala-Ala-Ala 4-nitroanilide pH 7.4, 37°C Homo sapiens
6.8
-
 methoxysuccinyl-Ala-Ile-Pro-Met-4-nitroanilide pH 7.4, 37°C Homo sapiens
8.1
-
 acetyl-Ala-Ala-Pro-Val-4-nitroanilide pH 7.4, 37°C Homo sapiens
17
-
 methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide pH 7.4, 37°C Homo sapiens