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Literature summary for 3.4.21.37 extracted from

  • Starkey, P.M.; Barrett, A.J.
    Human lysosomal elastase. Catalytic and immunological properties (1976), Biochem. J., 155, 265-271.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.37

Inhibitors

Inhibitors Comment Organism Structure
acetyl-Ala-Ala-Ala-Ala-CH2Cl
-
 Homo sapiens
acetyl-Ala-Ala-Pro-Ala-CH2Cl
-
 Homo sapiens
Cys
-
 Homo sapiens
diisopropyl phosphorofluoridate
-
 Homo sapiens
gold thiomalate inhibition is abolished by 1.0 M KCl Homo sapiens
NaCl 1.0 M, 50% inhibition Homo sapiens
ovomucoid chicken ovomucoid; turkey ovomucoid Homo sapiens
phenylmethylsulfonyl fluoride
-
 Homo sapiens
tosyl-Lys-CH2Cl weak Homo sapiens
Trypsin inhibitor lima-bean trypsin inhibitor; soya-bean trypsin inhibitor Homo sapiens
ZnSO4
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Homo sapiens 5764
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-(chloroacetyl)-3-naphthoic acid o-toluidide + H2O
-
 Homo sapiens ?
-
 ?
azocasein + H2O
-
 Homo sapiens ?
-
 ?
benzyloxycarbonyl-L-Ala 2-naphthyl ester + H2O
-
 Homo sapiens benzyloxycarbonyl-Ala + 2-naphthol
-
 ?
Elastin + H2O
-
 Homo sapiens ?
-
 ?
tert-butyloxycarbonyl-Ala-2-naphthyl ester + H2O
-
 Homo sapiens tert-butyloxycarbonyl-Ala + 2-naphthol
-
 ?
tert-butyloxycarbonyl-Ala-4-nitrophenyl ester + H2O
-
 Homo sapiens tert-butyloxycarbonyl-Ala + 4-nitrophenol
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.2 9.2 hydrolysis of azocasein or benzyloxycarbonyl-L-Ala 2-naphthyl ester Homo sapiens