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Literature summary for 3.4.21.36 extracted from
- Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond (2009), J. Am. Chem. Soc., 131, 11033-11040.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| PPE in complex with peptidic inhibitor FR130180 to 1.65 A resolution by neutron crystallography and 1.20 A resolution by X-ray crystallography at ambient temperature | Sus scrofa |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| FR130180 | i.e. 4-([(S)-1-[((S)-2-[[(RS)-3,3,3-trifluoro-1-isopropyl-2-oxopropyl]-aminocarbonyl]pyrrolidin-1yl)carbonyl]-2-methylpropyl]aminocarbonyl) benzoic acid | Sus scrofa |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | P00772 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Sus scrofa | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| elastase | - |
Sus scrofa |
| PPE | - |
Sus scrofa |
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Release 2023.1 (January 2023)
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