Any feedback?
Literature summary for 3.4.21.35 extracted from
- Tissue kallikrein protects cortical neurons against hypoxia/reoxygenation injury via the ERK1/2 pathway (2011), Biochem. Biophys. Res. Commun., 407, 283-287.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | tissue kallikrein administration can remarkably alleviate hypoxia/reoxygenation-induced neuronal injury by reduction of lactate dehydrogenase release and promotion of neuron viability | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebral cortical neuron | - |
Rattus norvegicus | - |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | tissue kallikrein prevents neurons from hypoxia/reoxygenation damage by influencing the activity of bradykinin B2 receptor followed by activating the ERK1/2 signal pathway, and thus promoting the survival of cortical neurons subjected to ischemia/reperfusion insults | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
