Literature summary for 3.4.21.35 extracted from

Weber, W.; Buck, F.; Meyer, A.; Hilz, H.
Prostate specific antigen: one out of five disulfide bridges determines inactivation by reduction (2009), Biochem. Biophys. Res. Commun., 379, 1101-1106.

Search for more literature for 3.4.21.35

Inhibitors

Inhibitors	Comment	Organism	Structure
(tris[2-carboxyethyl] phosphine) and dihydro-lipoic acid	13% residual activity at 3 mM	Homo sapiens
beta-mercaptoethanol	65% residual activity at 15 mM	Homo sapiens
dihydrolipoate	35% residual activity at 3 mM	Homo sapiens
dithiothreitol	complete inhibition at 3 mM	Homo sapiens
glutathione	16% residual activity at 15 mM	Homo sapiens
additional information	ascorbate is devoid of inactivating potential	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Zn2+-nitrilotriacetic acid agarose column chromatography	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
seminal plasma	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-methoxysuccinyl-Arg-Pro-Tyr-4-nitroanilide + H2O	-	Homo sapiens	N-methoxysuccinyl-Arg-Pro-Tyr + 4-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
hK3	-	Homo sapiens
prostate specific antigen	-	Homo sapiens
PSA	-	Homo sapiens

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Release 2023.1 (January 2023)