Inhibitors | Comment | Organism | Structure |
---|---|---|---|
decasodium 1,2,3,4,6-pentakis-O-[3,5-bis(sulfonatooxy)benzoyl]-beta-D-threo-hexopyranose | complete inhibition at 1 mg/ml | Homo sapiens | |
decasodium 1,2,3,4,6-pentakis-O-[4-hydroxy-3,5-bis(sulfonatooxy)benzoyl]-beta-D-threo-hexopyranose | complete inhibition at 0.2 mg/ml | Homo sapiens | |
additional information | not inhibited by unfractionated heparin, enoxaparin, fondaparinux, sucrose octasulfate, chondroitin sulfate A, dermatan sulfate, and chondroitin sulfate C | Homo sapiens | |
sulfated pentagalloyl beta-D-glucopyranoside | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor IX + H2O | Homo sapiens | - |
activated factor IX + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor IX + H2O | - |
Homo sapiens | activated factor IX + ? | - |
? | |
L-Glu-L-Glu-L-Pro-L-Arg-4-nitroanilide + H2O | S-2366 | Homo sapiens | L-Glu-L-Glu-L-Pro-L-Arg + 4-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
factor XIa | - |
Homo sapiens |
FXIa | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0005 | - |
at pH 7.4 and 37°C | Homo sapiens | decasodium 1,2,3,4,6-pentakis-O-[4-hydroxy-3,5-bis(sulfonatooxy)benzoyl]-beta-D-threo-hexopyranose | |
0.0014 | - |
at pH 7.4 and 37°C | Homo sapiens | decasodium 1,2,3,4,6-pentakis-O-[3,5-bis(sulfonatooxy)benzoyl]-beta-D-threo-hexopyranose |