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Literature summary for 3.4.21.26 extracted from

  • Sharma, K.K.; Ortwerth, B.J.
    Purification and characterization of prolyl oligopeptidase from bovine lens (1994), Exp. Eye Res., 59, 107-116.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
diisopropylfluorophosphate
-
Bos taurus
Elastatinal partially Bos taurus
N-ethylmaleimide
-
Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
72000
-
1 * 72000, SDS-PAGE Bos taurus
72000 74000 gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
lens
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.87
-
-
Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DRVYIHPF + H2O
-
Bos taurus DRVYIHP + L-Phe
-
?
FVNEHLCGSHLVQALTLVCGQRGFFYTPLA + H2O
-
Bos taurus FVNEHLCGSHLVQALTLVCGQRGFFYTP + LA
-
?
ISRPPGFSPFR + H2O
-
Bos taurus ISRPP + GFSPFR
-
?
Me-O-succinyl-Ala-Ala-Val p-nitroanilide + H2O
-
Bos taurus Me-O-succinyl-Ala-Ala + Val p-nitroanilide
-
?
succinyl-Gly-Pro-4-methylcoumarin 7-amide + H2O
-
Bos taurus ?
-
?
tert-butyloxycarbonyl-Ala-Ala p-nitroanilide + H2O
-
Bos taurus ?
-
?
tert-butyloxycarbonyl-Ala-Ala-Pro-Ala p-nitroanilide + H2O
-
Bos taurus tert-butyloxycarbonyl-Ala-Ala-Pro + Ala + p-nitoaniline
-
?
VHLTPVGL + H2O
-
Bos taurus VHLTP + VGL
-
?

Subunits

Subunits Comment Organism
monomer 1 * 72000, SDS-PAGE Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
Bos taurus