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Literature summary for 3.4.21.26 extracted from

  • Hannula, M.J.; Myoehaenen, T.T.; Tenorio-Laranga, J.; Maennistoe, P.T.; Garcia-Horsman, J.A.
    Prolyl oligopeptidase colocalizes with alpha-synuclein, beta-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinsons and Alzheimers diseases (2013), Neuroscience, 242, 140-150.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
KYP-2047
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-synuclein + H2O Homo sapiens
-
?
-
?
beta-amyloid + H2O Homo sapiens
-
?
-
?
additional information Homo sapiens prolyl oligopeptidase colocalizes with alpha-synuclein, beta-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinsons and Alzheimers diseases ?
-
?
tau protein + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-
hippocampus
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-synuclein + H2O
-
Homo sapiens ?
-
?
beta-amyloid + H2O
-
Homo sapiens ?
-
?
additional information prolyl oligopeptidase colocalizes with alpha-synuclein, beta-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinsons and Alzheimers diseases Homo sapiens ?
-
?
N-carbobenzoxy-Gly-L-Pro-7-amido-4-methylcoumarin + H2O
-
Homo sapiens N-carbobenzoxy-Gly-L-Pro + 7-amino-4-methylcoumarin
-
?
tau protein + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PEP
-
Homo sapiens
POP
-
Homo sapiens
PREP
-
Homo sapiens
prolyl endopeptidase
-
Homo sapiens