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Literature summary for 3.4.21.26 extracted from

  • Olivo, R.A.; Nascimento, N.G.; Teixeira, C.F.; Silveira, P.F.
    Methotrexate and cyclosporine treatments modify the activities of dipeptidyl peptidase IV and prolyl oligopeptidase in murine macrophages (2008), Clin. Dev. Immunol., 2008, 794050.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.26

Activating Compound

Activating Compound Comment Organism Structure
methotrexate
-
 Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-Pro-prolinal
-
 Mus musculus
cyclosporine A the activating effect of methotrexate dominates the inhibitory effect of cyclosporine A Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
bradykinin + H2O Mus musculus
-
 ?
-
 ?
Substance P + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 male Swiss strain mice
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Gly-Pro-beta-naphthylamide + H2O
-
 Mus musculus benzyloxycarbonyl-Gly-Pro + 2-naphthylamine
-
 ?
bradykinin + H2O
-
 Mus musculus ?
-
 ?
Gly-Pro-4-methoxy-beta-naphthylamide + H2O
-
 Mus musculus Gly-Pro + 4-methoxy-beta-naphthylamine
-
 ?
Substance P + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
POP
-
 Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mus musculus