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Literature summary for 3.4.21.26 extracted from

  • Lee, J.H.; Lee, S.Y.; Lee, K.S.; Jang, H.J.; Lee, K.H.; Hahn, T.R.; Paik, Y.S.
    Prolyl endopeptidase inhibitors from the leaves of Ginkgo biloba (2004), Planta Med., 70, 1228-1230.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
6-(10Z-heptadecenyl)salicylic acid isolated from leaves of Ginkgo biloba, noncompetitive, 50% inhibition at 0.00062 mM Elizabethkingia meningoseptica
6-(8Z-pentadecenyl)salicylic acid isolated from leaves of Ginkgo biloba, noncompetitive, 50% inhibition at 0.00086 mM Elizabethkingia meningoseptica
oleic acid 50% inhibition at 0.031 mM Elizabethkingia meningoseptica
salicylic acid 50% inhibition at 1.65 mM Elizabethkingia meningoseptica
Z-L-Pro-prolinal 50% inhibition at 0.0000022 mM Elizabethkingia meningoseptica

Organism

Organism UniProt Comment Textmining
Elizabethkingia meningoseptica
-
commercial preparation
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Gly-L-Pro-4-nitroanilide + H2O
-
Elizabethkingia meningoseptica ?
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0008
-
6-(10Z-heptadecenyl)salicylic acid pH 7.0, 37°C Elizabethkingia meningoseptica
0.00087
-
6-(8Z-pentadecenyl)salicylic acid pH 7.0, 37°C Elizabethkingia meningoseptica