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Literature summary for 3.4.21.26 extracted from

  • Matysiak-Budnik, T.; Candalh, C.; Cellier, C.; Dugave, C.; Namane, A.; Vidal-Martinez, T.; Cerf-Bensussan, N.; Heyman, M.
    Limited efficiency of prolyl-endopeptidase in the detoxification of gliadin peptides in celiac disease (2005), Gastroenterology, 129, 786-796.
    View publication on PubMed

Application

Application Comment Organism
medicine enzyme at 20 mU/ml can partly degrade gliadin peptides in vitro and ex vivo and decreases the amount of intact peptides crosing the intestinal biopsy specimens of celiac disease patients but cannot prevent the intestinal passage of toxic or immunostimulatory metabolites. Enzyme concentrations of at least 500 mU/ml are required to achieve full detoxification Elizabethkingia meningoseptica

Organism

Organism UniProt Comment Textmining
Elizabethkingia meningoseptica
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